Активность

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Lower respiratory tract infections (LRTIs) are one of the leading causes of infectious disease mortality worldwide. BAY-61-3606 concentration The aims of the study were to determine the incidence of hospitalizations due to LRTIs, and to analyze the clinical outcomes of the hospitalized patients.

An observational study of hospitalizations due to LRTIs (pneumonia and acute bronchitis/bronchio-litis) in Spain from 1997 to 2018 was carried out. Data were extracted from the national information system for hospital data.

Overall, 3.5?% (IQR 3.4-3.5?%) of total hospitalizations were caused by LRTIs, with a median incidence of 31.2 (IQR 27.8-33.0) per 10,000 inhabitants/year. The median incidence was higher for pneumonia than for acute bronchi-tis/bronchiolitis cases (22.2; IQR 19.1-23.5 vs. 9.0; IQR 8.4-9.6 per 10,000 inhabitants/year; p?<?0.001) and increased by 65.7?% from 1997 to 2018. A 41.2?% of the hospitalizations due to LRTIs took place amongst people over 74 years. The median length of stay was 8.9 days (IQR 7.6-10.4) and was higher for hospitalizations due to pneumonia than for acute bronchi-tis/bronchiolitis (9.5 days; IQR 8.3-10.6 vs. 5.7; IQR 5.5-6.2; p?<?0,001). In 89.1?% of total hospitalizations due to LRTIs, patients were discharged home. In-hospital mortality was 6.8?%, with 9,380 deaths (IQR 8,192-10,157) per year. Mortality was higher for pneumonia (9.0 vs. 1.7?%; p?<?0.001) and doubled from 1997 to 2018 (5,257 deaths in 1997 and 10,514 in 2018). The 75.5?% of the deaths occurred amongst people over 74 years.

LRTIs are associated with a high morbi-mortality in Spain. Effective measures that can contribute towards the prevention and treatment of LRTIs need to be adopted.

LRTIs are associated with a high morbi-mortality in Spain. Effective measures that can contribute towards the prevention and treatment of LRTIs need to be adopted.

Physiotherapy is postulated as an effective treatment after total knee arthroplasty (TKA). The objective of the study was to assess the efficacy of hydrotherapy versus gym kinesitherapy during the second phase of treatment in TKA patients, with regard to the improved gait test, pain, stiffness, joint balance, muscle strength and inflammation.

A controlled and randomized trial was carried out. TKA patients received a first rehabilitative phase (15 60-minutes sessions) at the gym. In the second phase (15 40-minute sessions), one group performed physiotherapy in a gym and another in a swimming pool. Different variables were assessed (basal, after 15 and after 30 ses-sions) functional capacity, pain and stiffness with WOMAC index, joint balance with goniometer; muscle strength with Lovett scale, and result of 6-minute gait test.

A total of 115 patients participated, 59 (51.3%) in the gym group and 56 (48.7?%) in the pool group. After the second phase of re-habilitation, higher clinical improvements were observed in the pool group, with statistically significant differences in pain (p?=?0.005), stiffness (p?=?0.010), joint balance (p?=?0.027) and muscle strength (p?=?0.049) in the operated knee, and in the result of the 6-minute gait test (p?=?0.002).

In TKA patients, hydrotherapy during the second phase of rehabilitative treatment was more effective than gym physiother-apy in terms of improved pain, stiffness, joint balance, muscle strength and gait testing.

In TKA patients, hydrotherapy during the second phase of rehabilitative treatment was more effective than gym physiother-apy in terms of improved pain, stiffness, joint balance, muscle strength and gait testing.

The purpose of this study was to examine the specific characteristics that were directly linked to menopausal symptoms of midlife women from four major racial/ethnic groups in the United States using a decision tree analysis.

This was a secondary analysis of the data from 1,027 midlife women from 2 larger Internet-based studies. The parent studies used the Midlife Women’s Symptom Index with multiple questions on background characteristics and health and menopausal status. The data were analyzed using ANOVA and decision tree analyses.

Across all the racial/ethnic groups, menopausal stage and country of birth were significantly related to the total number and total severity scores of menopausal symptoms (P < 0.001). In each racial/ethnic group, different combined characteristics of the participants were closely linked to the total number and total severity scores of menopausal symptoms (P < 0.05). For instance, in African Americans, the total severity scores of menopausal symptoms increased among those who were postmenopausal (P < 0.001), US born (P < 0.001), and with low family income (P = 0.030).

Specific risk groups by the combined characteristics need to be considered in future practice with midlife women.

Specific risk groups by the combined characteristics need to be considered in future practice with midlife women.The high theoretical lithium storage capacity of Sn makes it an enticing anode material for Li-ion batteries (LIBs); however, its large volumetric expansion during Li-Sn alloying must be addressed. Combining Sn with metals that are electrochemically inactive to lithium leads to intermetallics that can alleviate volumetric expansion issues and still enable high capacity. Here, we present the cycling behavior of a nanostructured MnSn2intermetallic used in LIBs. Nanostructured MnSn2is synthesized by reducing Sn and Mn salts using a hot injection method. The resulting MnSn2is characterized by x-ray diffraction and transmission electron microscopy and then is investigated as an anode for LIBs. The MnSn2electrode delivers a stable capacity of 514 mAh g-1after 100 cycles at a C/10 current rate with a Coulombic efficiency >99%. Unlike other Sn-intermetallic anodes, an activation overpotential peak near 0.9 V versus Li is present from the second lithiation and in subsequent cycles. We hypothesize that this effect is likely due to electrolyte reactions with segregated Mn from MnSn2.